CARDIOVASCULAR AND METABOLIC OUTCOMES ASSOCIATED WITH MODERATE-TO-SEVERE ATOPIC DERMATITIS: A SYSTEMATIC REVIEW AND META-ANALYSIS

Cardiovascular and metabolic outcomes associated with moderate-to-severe atopic dermatitis: A systematic review and meta-analysis

Background: Chronic systemic inflammation in individuals with moderate-to-severe atopic dermatitis (AD) potentially predisposes them to metabolic and cardiovascular diseases.Nevertheless, evidence with regard to such association is limited.Objective: To assess the association between metabolic and cardiovascular outcomes and moderate-to-severe AD.M

read more

A novel cell-based screen identifies chemical entities that reverse the immune-escape phenotype of metastatic tumours

Genetic and epigenetic events have been implicated in the downregulation of the cellular antigen processing and presentation machinery (APM), which in turn, has been associated with cancer evasion of the immune system.When these essential components are lacking, cancers develop the ability to subvert host immune surveillance allowing cancer cells t

read more

Understanding the sexual recruitment of one of the oldest and largest organisms on Earth, the seagrass Posidonia oceanica.

The seagrass Posidonia oceanica is considered one of the oldest and largest living organisms on Earth.Notwithstanding, given the difficulty of monitoring its fruits and seeds in Bias Tools the field, the development of P.oceanica during its sexual recruitment is not completely understood.We studied the stages of development of P.oceanica seeds from

read more